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Effect of Chitosan, Aluminum Oxide and Silver Nanoparticles on Antibacterial, Deodorizing and Moisture Absorption Properties of Nonwoven Polyester Fabrics for Use in Medical Textiles
Mohammad Khajeh Mehrizi , Hasan Mashroteh, Narges Nabizadeh Moghadam Noghabi,
Volume 10, Issue 4 (Jul-Aug 2016 2016)
Abstract

ABSTRACT

         Background and Objective: Hospital clothing and textiles have a great role in providing medical services to patients. Hospital services would not be possible without using these textiles. The aim of this study was to prepare non-woven polyester for use in medical textiles.

         Methods: In this study, most important expected properties of hospital clothing were created on polyester fabrics via various stages of finishing using chemicals such as calcium chloride, sodium alginate, chitosan and nanoparticles of silver nitrate and aluminum oxide. Antibacterial (activity against Staphylococcus aureus), deodorizing and wicking properties of samples were evaluated using nano-biomaterials via standard tests.

          Results: The water absorption rate of nonwoven samples that were finished with chitosan significantly improved. The results also showed favorable level of antimicrobial activity caused by silver nitrate and chitosan. In addition, deodorizing activity was observed in all samples. However, silver nitrate-finished samples had higher deodorizing activity. The capillary action of all samples reduced after completion of all finishing procedures.

          Conclusion: The results show that the use of chitosan and alginate along with nanoparticles of silver nitrate and aluminum oxide can be effective in achieving the desired properties of medical textiles.

        Keywords: Medical textiles, antibacterial substances, chitosan, silver nitrate.


Attenuation of glucose mediated DNA glycation by Tamarix aphylla extract
Parisa Hasanein , Fahime Javadi Hedaiat Abad, Mousa Bohlooli , Mostafa Khajeh , Sedigheh Esmaielzadeh Bahabadi , Neda Poormolaei ,
Volume 19, Issue 2 (3-2025)
Abstract
Background: DNA glycation, a process where Glc non-enzymatically binds to DNA, is implicated in various detrimental effects, including strand breaks, mutations, and altered gene expression. This damage is considered a significant contributor to the pathogenesis of diabetes mellitus and its associated complications. Consequently, there has been increasing interest in identifying antiglycation agents as a strategy for preventing and mitigating these complications. Prior research has indicated that extracts from Tamarix aphylla (T. aphylla) leaves possess antidiabetic properties. Therefore, this study aimed to investigate, for the first time, the impact of T. aphylla extract on Glc-mediated DNA glycation.
Methods: DNA samples were incubated with Glc over a four-week period. Subsequently, the modulatory effects of T. aphylla on Glc-induced DNA structural alterations were investigated employing a range of analytical techniques. These methodologies encompassed ultraviolet-visible (UV-Vis) spectroscopy, fluorescence spectroscopy, circular dichroism (CD) spectroscopy, and agarose gel electrophoresis.
Results: The results obtained from UV–Vis and fluorescence spectroscopy demonstrated that T. aphylla extract led to a reduction in the formation of DNA-advanced glycation end products (AGEs). Furthermore, CD spectroscopy and agarose gel electrophoresis analyses indicated that the structural alterations of glycated DNA were diminished in the presence of T. aphylla extract.
Conclusion: Based on the evidence presented, T. aphylla demonstrates protective properties against DNA glycation. Consequently, pending further rigorous investigation, it may represent a potentially valuable therapeutic agent for mitigating the detrimental consequences of glycation, particularly in environments characterized by elevated Glc concentrations and hyperglycemic states.

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