Search published articles


Showing 3 results for baniaghil
Prevalence of HIV, HCV, HBV in Blood Donors of Golestan Province, Iran, 2012 - 2013
Hosseini, Ma, Baniaghil, Ss, Mahmoodi, E, Bagheri Sani, Y, Dahbashi, Gh,
Volume 9, Issue 3 (Jul,Aug2015[PERSIAN] 2015)
Abstract

Abstract

Background and Objective: The donor selection and screening of blood donors for infectious factors  is the main  target of blood transfusion organization.  this study aimed at  determining the prevalence of HCV, HBV and HIV in blood donors  of  Golestan province , from 2012 to 2013.

Material and Methods: This cross-sectional study was conducted on all files of blood donors with positive lab results in  Golestan Blood Transfusion Services. The  test results, demographic characteristics and the  Prevalence of  hepatitis B and C and HIV were determined . The results were analyzed by SPSS software.

Results: The blood donors were  47,830 and 45,811 in 2012  and 2013, respectively. The  Prevalence of HBV in 2012  was%0. 299 and in  2013 %0. 284; of HCV % 0. 06  in 2012  and   % 0.05 in 2013,  and the prevalence of  both HCV and HIV totally was  0. 001percent in  two years of study. The  highest rate of positive case was among the first time donors, married and  in  those with less than  high school education  (P<0.05).

Conclusion: Regarding the high rate of positive cases  among the first-time blood donors, married and less educated, it is recommended that public media be used  for giving information to control communicable infections.

Keyword: HBV; HCV; HIV; Prevalence; Blood Donors .


Evaluation prevalence of Rh system major antigens (D, C, c, E, e) and their phenotypes in blood donors of Golestan province, Iran
Seyed Sadegh Baniaghil, Fardin Balochi , Alireza Ahmadi,
Volume 18, Issue 3 (May-Jun 2024)
Abstract
Background: The understanding of blood group phenotypes is currently limited to the ABO and Rh blood group systems. This study aimed to determine the frequency of Rh system antigens (D, C, c, E, e) and the phenotypes of the system in blood donors. Identifying the blood group phenotypes of donors in any population is important for improving healthcare services and better serving patients.
Methods: This descriptive study was carried out on 575 donors (Turkmen and Fars) in blood transfusion centers in Golestan Province, Iran. A cell suspension (3-5%) from each sample was prepared in normal saline and exposed to Rh system antisera using the haemagglutination technique. The Rh phenotype was then determined based on the most common genotype.
Results: For the Rh system, the antigen frequencies of D, C, c, E, and e were 87.76%, 73.6%, 72.1%, 30.83%, and 93.59%, respectively. The most common phenotypes among the Turkmen and Fars donors were R1R1, R1r, and rr, respectively, while the least common phenotypes were R2Rz and ryry. The phenotypes r'r' and ryry were not detected in the Turkmen donors, and the phenotype r''r' was not identified in the Fars donors.
Conclusion: Identifying the prevalence of blood group antigens in donors from each region is crucial for organizing negative antigen blood units, preparing compatible blood for multitransfused patients, and preventing the development of alloantibodies in these patients.
 

Evaluation of red cell alloantibodies in thalassemia major patients referred to blood transfusion center of Golestan province, Iran
Seyed Sadegh Baniaghil, Fardin Balochi, Ereste Kazak,
Volume 19, Issue 3 (7-2025)
Abstract
Background: One of the major complications in thalassemia patients is alloimmunization, which is antibody production by the patient against transfused RBCs (red blood cells). In the present study, the frequency of alloantibodies in thalassemia patients was investigated.
Materials and Methods: In this cross-sectional retrospective study, the study was performed on ninety nine multi-transfused thalassemia patients, antibody screening test was carried out using three cell-panel. Positive patients were followed up for antibody identification using 11-cell panel. The information was finally analyzed using SPSS software version 16.0.
Results: Out of ninety-nine cases, 53 were female (53.53 %) and 46 male (46.46 %). The patient’s age mean was 29.22±10.46 years with 2 to 61 years age range. Only 5.05% (N=5) had developed alloantibodies. The most common alloantibodies were Anti-D, Anti-E, Anti-c and Anti-K. No significant correlation was seen between the presence of alloantibody and age, sex, blood type and spleen condition.
Conclusion: Antibody production against RBC antigens is a common problem in multi-transfused thalassemia patients. Compatibility between antigens of Kell and Rh blood group systems in donors and recipients can be one of the useful ways to prevent alloimmunization of blood recipients and the production of unexpected antibodies against donor’s red blood cells.
Page 1 from 1     

© 2007 All Rights Reserved | Medical Laboratory Journal

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.