Shahnaz Halimi , Pegah Shakib , Elham Mehrabnejad , Faranak Rezaei , Somayeh Delfani ,
Volume 19, Issue 6 (11-2025)
Abstract
Background: The widespread increase in the prevalence of antibiotic resistance in bacteria is considered one of the biggest problems in the global health and treatment system today. Therefore, this study was conducted to investigate the prevalence and antibiotic resistance pattern of bacteria isolated from blood cultures at Shahid Rahimi Hospital in Khorramabad in 2018.
Methods: This cross-sectional study investigated blood cultures of patients admitted to Shahid Rahimi Hospital from June to December 2018. The disc diffusion method was used according to CLSI instructions, and the data were analyzed using SPSS software.
Results: Out of a total of 2591 blood culture samples, 247 blood culture samples were positive. The highest frequency was related to the emergency department (62%) and ICU (23%), and the lowest frequency was related to the children's department (2.4%). Among the tested samples, 28% were Gram-negative bacilli and 72% were Gram-positive cocci. The most common Gram-negative and Gram-positive bacteria were Escherichia coli (38%) and Staphylococcus epidermidis (54.2%), respectively. Among Gram-negative bacteria, the highest level of resistance was seen in Acinetobacter baumannii strains, which showed resistance to all antibiotics. Among Gram-positive bacteria, the highest resistance of Streptococcus group D strains to the antibiotic erythromycin (92%) was reported.
Conclusion: The prevalence of antibiotic resistance in common microorganisms isolated from blood cultures in different departments is worrying, and choosing an effective drug to eliminate these bacteria by performing accurate laboratory tests is of particular importance.
goums.ac.ir
yahoo.com