Maryam Enshaei Mojarad, Hajar Abbaszadeh, Parvin Farzanegi,
Volume 19, Issue 3 (7-2025)
Abstract
Background and objectives: The purpose of this study was to investigate the effect of a period of intense functional training on some markers of m2 macrophages (IL-10, Dectin-1, IL-1Ra) in prediabetic obese women so that the effect of this type of exercise training on some markers of m2 macrophages in women check pre-diabetic obesity.
Methods: 30 eligible female volunteers aged 35-40 years were selected. Based on individual characteristics, the subjects were homogeneously divided into two groups: 1) the control (15 people) and 2) the training group (15 people). In this research, for High-Intensity Functional Training (HIFT) based on CrossFit training protocols, squat, deadlift, press, barbell, dumbbell, medicine ball exercise, fixed bar, rotating kettlebell, and aerobic exercises (such as running, rope pulling) Weight-bearing exercises (such as horizontal pull-ups, squats) and weight-lifting exercises (such as front squats, kettlebell swings) were used on a WOD (workout of the day) basis.
Results: The results showed that High-Intensity Functional Training causes a significant decrease in Dectin-1 and a significant increase in IL-10, and IL-1Ra in prediabetic obese women.
Conclusion: It seems that in the present study, 16 weeks of high-intensity functional training improved the secretion and function of m2 macrophage markers (IL-10, Dectin-1, IL-1Ra) in prediabetic obese women.
